Hepatoid Adenocarcinoma of the Gall Bladder-A Rare Variant
Published: August 1, 2015 | DOI: https://doi.org/10.7860/JCDR/2015/.6324
Nalli. R. Sumitra Devi, R. Sathyalakshmi, J. Devi, S. Marylilly
1. Professor, Department of Pathology, Stanley Medical College, Tamil Nadu Dr. MGR Medical University, India.
2. Assistant Professor, Department of Pathology, Stanley Medical College, Tamil Nadu Dr. MGR Medical University, India.
3. Postgraduate, Department of Pathology, Stanley Medical College, Tamil Nadu Dr. MGR Medical University, India.
4. HOD & Professor, Department of Pathology, Stanley Medical College, Tamil Nadu Dr. MGR Medical University, India.
Correspondence
Dr. R. Sathyalakshmi,
No: 2, 4th street, Srilakshmi nagar, Velachery, Chennai-600042, India.
E-mail: sathyalakshmi.ramu4@gmail.com
Hepatoid adenocarcinoma is a rare variant of extra hepatic adenocarcinoma, consisting of foci of both adenomatous and hepatocellular differentiation with morphological and functional resemblance to hepatocellular carcinoma and hence correct diagnosis is a challenge. The most frequent site is stomach. We present this case of hepatoid carcinoma of the gallbladder for its rarity and difficulty in diagnosis which on histology showed papillae, sheets and trabaculae of polygonal cells with eosinophilic cytoplasm and vesicular nuclei with prominent nucleoli with adjacent foci showing high grade dysplasia.
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